منابع مشابه
Impact of Environmental Chemicals on Lung Development
BACKGROUND Disruption of fundamental biologic processes and associated signaling events may result in clinically significant alterations in lung development. OBJECTIVES We reviewed evidence on the impact of environmental chemicals on lung development and key signaling events in lung morphogenesis, and the relevance of potential outcomes to public health and regulatory science . DATA SOURCES...
متن کاملInfluences of Environmental Chemicals on Atopic Dermatitis
Atopic dermatitis is a chronic inflammatory skin condition including severe pruritus, xerosis, visible eczematous skin lesions that mainly begin early in life. Atopic dermatitis exerts a profound impact on the quality of life of patients and their families. The estimated lifetime prevalence of atopic dermatitis has increased 2~3 fold during over the past 30 years, especially in urban areas in i...
متن کاملEpigenetics and environmental chemicals.
PURPOSE OF REVIEW Epigenetics investigates heritable changes in gene expression occurring without changes in DNA sequence. Several epigenetic mechanisms, including DNA methylation, histone modifications, and microRNA expression, can change genome function under exogenous influence. Here, we review current evidence indicating that epigenetic alterations mediate toxicity from environmental chemic...
متن کاملEnvironmental chemicals targeting thyroid.
Thyroid hormones (THs) are required for normal brain and somatic development and for the proper regulation of physiology in both children and adults. Thyroid function is controlled by the dynamic interrelationships between the hypothalamus, the pituitary and the thyroid. These dynamic relationships maintain circulating levels of THs within a narrow range under normal conditions. Normally, there...
متن کاملEnvironmental persistence of chemicals.
BACKGROUND The hazard criterion of persistence as it applies to chemicals in the environment is reviewed and discussed. This quantity can not be measured directly in the environment, thus it must be estimated using models that synthesise information on chemical half-lives and partitioning properties, the nature of the environment and how the chemical is released into the environment. MAIN FEA...
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ژورنال
عنوان ژورنال: Japan journal of water pollution research
سال: 1991
ISSN: 0387-2025
DOI: 10.2965/jswe1978.14.432